6533b7d2fe1ef96bd125e26e

RESEARCH PRODUCT

Antibodies for strain 2117-like vesiviruses (caliciviruses) in humans

Giovanni M. GiammancoAntonio LavazzaKrisztián BányaiFederica Di ProfioSimona De GraziaGianvito LanaveVito MartellaCanio BuonavogliaBarbara Di MartinoFulvio Marsilio

subject

AdultMaleSettore MED/07 - Microbiologia E Microbiologia ClinicaCancer ResearchAdolescentAntibodieCellAntibodies ViralAntibodiesCalicivirusesVesivirus strain 2117Young AdultCaliciviruseSeroepidemiologic StudiesVirologymedicineHumansVesivirusChildVesivirusAgedAged 80 and overbiologyStrain (chemistry)Infant NewbornInfantEnvironmental ExposureElisa assaySeroepidemiologic StudiesEnvironmental exposureMiddle AgedContaminationbiology.organism_classificationVirologyInfectious Diseasesmedicine.anatomical_structureChild Preschoolbiology.proteinFemaleAntibodies; Caliciviruses; Humans; Vesivirus strain 2117AntibodyHuman

description

The vesivirus strain 2117 has been identified as contaminant of bioreactors used for production of human drugs, due to possible contamination of the reagents used for cell cultivation. Using an ELISA assay, antibodies specific for 2117-like viruses were detected in 32/410 (7.8%) human sera, indicating exposure to these viruses.

yearjournalcountryeditionlanguage
2015-01-01Virus Research
https://doi.org/10.1016/j.virusres.2015.08.016