6533b7d2fe1ef96bd125eaba
RESEARCH PRODUCT
Carcinoma of the prostate. Guidelines for treatment: the role of antiandrogens.
G. DaricelloMichele Pavone-macalusoCarlo PavoneVincenzo SerrettaCacciatore Msubject
OncologyMalemedicine.medical_specialtyAntiandrogensmedicine.medical_treatmentUrologyImidazolidinesGeneral Biochemistry Genetics and Molecular BiologyFlutamideProstate cancerchemistry.chemical_compoundHistory and Philosophy of ScienceProstateInternal medicinemedicineCarcinomaHumansLibidobusiness.industryGeneral NeuroscienceCarcinomaImidazolesProstatic NeoplasmsAndrogen Antagonistsmedicine.diseaseFlutamidemedicine.anatomical_structurechemistryElevated transaminasesHormone therapybusinessdescription
Our preliminary experience shows that flutamide is effective in patients with stage C or D prostate cancer. Local and distant response rates are comparable to those obtained with "classic" hormone therapy. Libido and sexual potency generally are unaffected. Palliation of symptoms, which is frequent, is usually accompanied by improved performance status and quality of life. Side effects are slight or moderate, but elevated transaminase levels in patients with borderline liver insufficiency are possible.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1990-06-01 | Annals of the New York Academy of Sciences |