6533b7d2fe1ef96bd125eae2

RESEARCH PRODUCT

Lack of association between HLA specificities and Wilms' tumour.

P. GutjahrU. KnoopS. ZschiedrichW. HaaseK. G. Evers

subject

Maleeducation.field_of_studybusiness.industryMatched controlWilms tumourPopulationGermany WestWilms' tumorHuman leukocyte antigenDiseasemedicine.diseaseWilms TumorPhenotypeGene FrequencyHLA AntigensPediatrics Perinatology and Child HealthImmunologymedicineHumansFemaleeducationbusinessChildAllele frequency

description

HLA antigen distribution was determined in thirty patients with Wilms' tumour, and their frequencies compared with those of an ethnically matched control population. No statistically significant association was found between any single HLA antigen and Wilms' tumour disease. The value of prospective HLA typing studies, with special respect to genetic aspects, histopathological subgrouping and survival rate of Wilm's tumour patients is discussed.

yearjournalcountryeditionlanguage
1981-03-01European journal of pediatrics
10.1007/bf00441710https://pubmed.ncbi.nlm.nih.gov/6260503