6533b7d2fe1ef96bd125ec4e
RESEARCH PRODUCT
Myopathic form of arthrogryposis and microcirculation lesion.
Uta Burck-lehmannHans H. GoebelAnna Fidziańskasubject
ArthrogryposisArthrogryposisMalePathologymedicine.medical_specialtyVascular diseasebusiness.industryMusclesInfantAnatomyBlood Coagulation Disordersmedicine.diseaseThrombosisPathophysiologyMicrocirculationLesionNeurologyMuscular DiseasesmedicineHumansPlateletNeurology (clinical)medicine.symptombusinessNeutrophil aggregationdescription
A microvascular lesion characterized by extensive platelet aggregation, thrombosis, vascular damage with hemorrhages was found in the muscle of a 2-month-old boy with a myopathic form of the arthrogryposis syndrome. The lesion morphologically resembled the vascular leakage seen in immunologically mediated tissue injury. A degradative effect of proteases released during platelet and neutrophil aggregation on the muscle and joints is suggested.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1989-09-01 | Journal of the neurological sciences |