6533b7d2fe1ef96bd125f545
RESEARCH PRODUCT
Radiation-related superficial oral mucoceles : an under-recognized acute toxicity in head and neck cancer patients
Karina MoutinhoLuciana-estevam SimonatoKarina-morais FariaThais-bianca BrandaoAna-carolina Prado-ribeiroAlan-roger Santos-silvaWagner-gomes Silvasubject
AdultMalemedicine.medical_specialtyCross-sectional studymedicine.medical_treatmentMucoceleAsymptomaticHead and neck radiotherapymedicineCarcinomaHumansRadiation InjuriesGeneral DentistryAgedRetrospective StudiesOral Medicine and Pathologybusiness.industryResearchHead and neck cancerRetrospective cohort studyMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Acute toxicityRadiation therapyCross-Sectional StudiesOtorhinolaryngologyHead and Neck NeoplasmsUNESCO::CIENCIAS MÉDICASAcute DiseaseCarcinoma Squamous CellSurgeryFemaleRadiologymedicine.symptombusinessMouth Diseasesdescription
Background Acute toxicity is usually defined as adverse changes occurring immediately or a short time after the start of oncological treatment. Material and Methods Cross-sectional retrospective study performed with head and neck cancer patients who underwent radiotherapy from 2013 to 2016. Results Ten (1.2%) patients developed SOMs during radiotherapy, most (80%) of which were men with a mean age of 59.5 years at diagnosis. SOMs mainly affected the floor of the mouth (60%) between the fourth and the sixth weeks of radiation therapy. All lesions were asymptomatic and spontaneously ruptured approximately 9 days after diagnosis. Conclusions Although rare, SOMs may be regarded as an acute oral toxicity of head and neck radiotherapy. Key words:Superficial oral mucoceles; head and neck cancer; radiation toxicity, acute toxicity.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2018-03-19 |