6533b7d3fe1ef96bd1260104

RESEARCH PRODUCT

Relationship between Thyroid Status during the First Trimester of Pregnancy and Neonatal Well-Being

Maria Teresa Murillo-llorenteFrancisco Llorca-colomerMarcelino Pérez-bermejo

subject

Adultmedicine.medical_specialtyendocrine systemendocrine system diseasesThyroid GlandThyrotropin030209 endocrinology & metabolismlcsh:TX341-641APGAR scoreArticle03 medical and health sciences0302 clinical medicinegestationHypothyroidismnewbornPregnancymedicineHumans030212 general & internal medicineSodium Chloride DietaryPregnancyNutrition and DieteticsAnthropometryObstetricsbusiness.industryThyroidInfant NewbornPregnancy OutcomePrenatal Careiodine supplementsMaternal Nutritional Physiological Phenomenamedicine.diseaseApgar TestMicronutrientIodine deficiencyiodized saltPregnancy ComplicationsIodised saltPregnancy Trimester Firstmedicine.anatomical_structureDietary SupplementsGestationApgar scoreFemalebusinesslcsh:Nutrition. Foods and food supplyfetal well-beingFood ScienceIodine

description

Iodine is an essential micronutrient for the synthesis of thyroid hormones. The proper functioning of the thyroid axis is essential for the normal development of the nervous system, especially in the first trimester of gestation. The aim of the present study was to analyze the perinatal outcomes, anthropometry, and APGAR test scores of newborns and to relate them to maternal thyroid status. A total of 190 newborns participated in the study. No correlation was found between thyroid stimulating hormone (TSH) and maternal ioduria values in the first trimester of gestation with the weight or length of the newborn, or the APGAR score at one minute after birth. However, we found significant differences between the APGAR scores of children whose mothers had an iodine sufficiency level in the first trimester compared to the children of mothers with iodine deficiency. Similarly, the APGAR scores of children whose mothers had a TSH &gt

10.3390/nu13030872http://europepmc.org/articles/PMC7999325