6533b7d3fe1ef96bd12609eb

RESEARCH PRODUCT

Use of Thromboelastography in severe sepsis a case-control Study

Santi Maurizio RaineriA Di BenedettoL VentoM MilanaAndrea CortegianiFrancesca MontaltoL Marino

subject

medicine.medical_specialtymedicine.diagnostic_testbusiness.industrymedicine.medical_treatmentCase-control studyThromboelastography Severe Sepsis Septic ShockSettore MED/41 - AnestesiologiaLiver transplantationCritical Care and Intensive Care Medicinemedicine.diseaseClot formationThromboelastographySurgerySepsisCoagulationInternal medicineFibrinolysisPoster PresentationmedicineCardiologybusinessSevere sepsis

description

Thromboelastography (TEG) is a global test of coagulation that records the viscoelastic changes in blood during clot formation. Cardiosurgery and liver transplantation are established fields of application for TEG. Severe sepsis is often characterized by an imbalance of the haemostatic equilibrium between clot formation and fibrinolysis in favor of a procoagulant status, especially in the first phase. A hypocoagulant status due to coagulation factor consumption could occur later. In spite of this, the correlation between TEG and sepsis is not clearly established. Moreover, there are doubts about which TEG-detected variable is best correlated with sepsis. The aim of this study is to clarify this correlation.

10.1186/cc9864http://hdl.handle.net/10447/59025