6533b7d3fe1ef96bd1260af4

RESEARCH PRODUCT

Inspired supplemental oxygen reduces markers of oxidative stress during elective colon surgery.

Robert GreifJ. Garcia De La AsuncionJuan SastreF. J. BeldaJose ViñaG. Barber

subject

medicine.medical_specialtySupplemental oxygenchemistry.chemical_elementmedicine.disease_causeOxygenchemistry.chemical_compoundColonic DiseasesPostoperative ComplicationsColon surgeryMalondialdehydeRespirationmedicineHumansOxygen supplementationbusiness.industryOxygen Inhalation TherapyMalondialdehydeGlutathioneSurgeryOxygenOxidative StressSodium thiopentalTreatment OutcomechemistryAnesthesiaSurgerybusinessOxidative stressBiomarkersmedicine.drug

description

.Anaesthesia was induced with sodium thiopental andfentanyl, and maintained with sevoflurane. After inductionof anaesthesia, patients were randomly assigned 30 or80 per cent oxygen throughout surgery and for 6 hafterwards. During surgery, lungs were ventilated involume-controlled mode (10 ml/kg), whereas during the6 h afterwards respiration was spontaneous with an oxygenmask (16 l/min)

10.1002/bjs.5497https://pubmed.ncbi.nlm.nih.gov/17225211