6533b7d3fe1ef96bd12614e8

RESEARCH PRODUCT

Extent of resection and survival in glioblastoma multiforme

Giovanni Grasso

subject

Cancer Researchmedicine.medical_specialtybusiness.industryExtent of resectionmedicine.diseaseGross Total Resection03 medical and health sciences0302 clinical medicineOncologyextent of resection glioma gross total resection030220 oncology & carcinogenesisGliomaMedicineRadiologybusiness030217 neurology & neurosurgeryGlioblastoma

description

Brown and colleagues1 reported the results of a systematic review of the literature aimed in determining whether greater extent of resection (EOR) is associated with improved 1- and 2-year overall survival and 6-month and 1-year progression-free survival in patients affected by glioblastoma multiforme. The analysis revealed 37 studies suitable for inclusion. The authors found that gross total resection (GTR) for glioblastoma multiforme reduces 1- and 2-year mortality, thus supporting GTR over subtotal resection and biopsy.

yearjournalcountryeditionlanguage
2016-11-01
10.1001/jamaoncol.2016.3806http://hdl.handle.net/10447/397666