6533b7d3fe1ef96bd126153e

RESEARCH PRODUCT

Using the critical body residue approach to determine the acute toxicity of cadmium at varying levels of water hardness and dissolved organic carbon concentrations

Ari VäisänenVuokko MalkOlli-pekka PenttinenS. Penttinen

subject

Lumbriculus variegatusHealth Toxicology and Mutagenesis0211 other engineering and technologieschemistry.chemical_elementFresh WaterMetal toxicity02 engineering and technology010501 environmental sciences01 natural sciencesLethal Dose 50Dissolved organic carbonToxicity Tests AcuteAnimalsEcotoxicologyOligochaeta0105 earth and related environmental sciencesPollutant021110 strategic defence & security studiesCadmiumbiologyPublic Health Environmental and Occupational HealthGeneral Medicinebiology.organism_classificationPollutionCarbonAcute toxicitychemistryEnvironmental chemistryToxicityWater Pollutants ChemicalCadmium

description

Abstract The linkage between acute adverse effects of cadmium and internal cadmium levels were investigated for the oligochaete worm Lumbriculus variegatus in water at varying degrees of hardness and two different dissolved organic carbon (DOC) concentrations. The LC50s for the effect of cadmium on the survival of the worms greatly differed depending on water hardness and DOC. We found less variability in internal metal toxicity metrics (lethal residue; LR50s) than in external toxicity metrics (lethal concentration; LC50s): LC50s varied from 2.4 to 66.1 μmol/L, while LR50s varied only from 226 to 413 μmol/kg wet weight. The cadmium body burden appeared to be independent of exposure conditions. From our experimental data, a critical cadmium body residue (324±78 μmol/kg wet weight) associated with 50% lethality was derived. The protective role of DOC and water hardness against cadmium toxicity was evident.

yearjournalcountryeditionlanguage
2011-07-01Ecotoxicology and Environmental Safety
https://doi.org/10.1016/j.ecoenv.2011.03.017