6533b7d4fe1ef96bd1261c86

RESEARCH PRODUCT

ChemInform Abstract: Metal-Free Regioselective C-C Bond Cleavage in 1,3,5-Triazine Derivatives of β-Diketones.

Maximilian N. KopylovichArmando J. L. PombeiroMatti HaukkaKamran T. MahmudovKamran T. Mahmudov

subject

chemistry.chemical_compoundAqueous solutionMetal free135-TriazineChemistryCyanuric chlorideRegioselectivityGeneral MedicineMedicinal chemistryBond cleavageAdduct

description

The reaction of cyanuric chloride (I) with 3 equivalents of ketones (II) in the presence of 3 equivalents of KOH affords adducts (IV), which are converted into deacylated derivatives (III) by treatment with aqueous HCl solution in MeOH.

https://doi.org/10.1002/chin.201425188