6533b7d4fe1ef96bd1261fcb

RESEARCH PRODUCT

Retrospective study of 289 odontogenic tumors in a Brazilian population

Leorik-pereira Da SilvaMarianna-sampaio SerpaJefferson-da-rocha TenorioAna-paula Veras-sobralGeorge-joão-ferreira Do NascimentoEmanuel-sávio De Souza-andrade

subject

AdultMalemedicine.medical_specialtyPathologyOdontologíaOdontogenic TumorsAmeloblastoma03 medical and health sciences0302 clinical medicineOdontomaparasitic diseasesMedicineHumansAmeloblastomaGeneral DentistryRetrospective StudiesOral Medicine and Pathologybusiness.industryResearchOdontomaRetrospective cohort study030206 dentistrymedicine.disease:CIENCIAS MÉDICAS [UNESCO]DermatologyCiencias de la saludOdontogenicOtorhinolaryngology030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASPublic universitySurgeryBrazilian populationFemalebusinessBrazil

description

Background: Odontogenic tumors (OTs) are considered important among oral lesions because of their clinicopathological heterogeneity, and variable biological behavior. This paper aims to determine the frequency and distribution of OTs, over a period of 10 years, at a public university in Northeastern Brazil and compare this data with previous reports. Material and Methods: We reviewed all cases of OTs from oral pathology laboratory of University of Pernambuco (UPE), from 2004 to 2014. Diagnoses were re-evaluated and the tumors were classified according to the latest (2005) World Health Organization Classification of Tumors. In addition, we searched in the English-language literature retrospective studies on OTs that used the same classification. Results: Within the total of 6028 oral biopsies, 289 (4.79%) were OTs. Of these, 287 (99.3%) were benign and 2 (0.7%) were malignant. The overall incidence was 31.1/million. Mandible-maxilla ratio was 2.5:1 and mean age 35 years. Keratocystic odontogenic tumor (KCOT) (34.6%) was the most frequent lesion, followed by ameloblastoma (AMB) (32.9%) and odontoma (ODO) (11.4%). Conclusions: OTs are uncommon neoplasms with geographic variation. Our clinicopathological features are according to literature. In the present study, KCOT was the most frequent one, showing that the new classification of OTs altered the distribution of these lesions and possibly made KCOT the most common OT observed in diagnostic services worldwide

yearjournalcountryeditionlanguage
2016-01-01Medicina Oral, Patología Oral y Cirugía Bucal
10.4317/medoral.21029http://europepmc.org/articles/PMC4867199