6533b7d4fe1ef96bd1263202
RESEARCH PRODUCT
MRI as the new reference standard in quantifying liver steatosis: the need for international guidelines.
Jean-pierre CercueilBoris Guiusubject
Malemedicine.medical_specialtymedicine.diagnostic_testbusiness.industryFatty liverGastroenterologyMagnetic resonance imagingmedicine.diseaseLipidsMagnetic Resonance ImagingFatty LiverLiver steatosismedicineLiver ironAnimalsHumansFemaleRadiologybusinessNuclear medicineReference standardsdescription
We read with great interest the paper by Raptis et al 1 regarding the quantification of liver steatosis by chemical-shift MRI. Chemical-shift imaging takes advantage of the difference in resonance frequency between water and fat (more precisely methylene, the most abundant group in triglycerides) to differentiate them. The dual-echo (in-phase/out-of-phase) MR technique used by the authors and derived from one of their previously published papers2 neglects T2* decay and assumes that the signal difference is due to fat–water interference alone.3 Yet, liver iron …
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2012-01-12 | Gut |