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RESEARCH PRODUCT

The cell nucleus. A study in Burgundy

Alexei ArnaoutovOleg N. DemidovOleg N. DemidovMary DassoVasilisa Aksenova

subject

lcsh:QH426-470media_common.quotation_subjectPhase separationArt history03 medical and health sciencesNeoplasmsmedicineAnimalsHumanslcsh:QH573-671nucleolusNuclear pore030304 developmental biologymedia_commonCell Nucleus0303 health scienceslcsh:Cytologynuclear pores030302 biochemistry & molecular biologyCell BiologyArtWilhelm Bernhard Workshop 2019lcsh:GeneticsMicroscopy ElectronCell nucleusmedicine.anatomical_structurelaminsRNANuclear transportNucleusLamin

description

ABSTRACT Wilhelm Bernhard’s revolutionary microscopy techniques helped him put forward the hypothesis of specialized compartmentalization of the nucleus. He also described for the first time the nuclear bodies and peri-chromatin fibrils, and demonstrated that these granules contain an RNA component. The tradition of biennial workshops, named after this great scientist, continues, and this year it took place in the heart of Burgundy, in Dijon, France (May 20–24, 2019, organized by INSERM UMR1231, UBFC), where well-fed participants emphasized the importance of viewing the cell nucleus as a hub of specialized colloidal compartments that orchestrate replication, transcription and nuclear transport.

https://doi.org/10.1080/19491034.2019.1649835