6533b7d5fe1ef96bd126495e
RESEARCH PRODUCT
Long-term UVB irradiation affects the immune functions of carp (Cyprinus carpio) and rainbow trout (Oncorhynchus mykiss).
Eveliina MarkkulaKaisa RikalainenHarri M. SaloIlmari Jokinensubject
CarpsTime FactorsUltraviolet RaysBiologyKidneyBiochemistryCyprinusAndrologyImmune systemAnimalsPhysical and Theoretical ChemistryPhytohemagglutininsCarpCells CulturedCell ProliferationHead KidneyPhagocytesurogenital systemAquatic animalGeneral MedicineAnatomybiology.organism_classificationRespiratory burstBlood chemistryOncorhynchus mykissRainbow troutdescription
The effects of long-term, low-dose ultraviolet B (UVB) radiation on immune functions of two fish species representing different taxonomic groups, carp (Cyprinus carpio) and rainbow trout (Oncorhynchus mykiss), were assessed in this study. The fish were exposed to 7, 20 or 60 mJ cm(-2) UVB three times per week, for 6 weeks. In carp, UVB exposure affected the respiratory burst activity of blood and head kidney phagocytes, differential blood leukocyte counts and blood chemistry. Phytohemagglutinin (PHA)-stimulated in vitro proliferation responses of blood and head kidney lymphocytes, however, remained unchanged. Rainbow trout tolerated the irradiations with fewer alterations, but significant changes were detected in blood chemistry and hematocrits of the irradiated fish. These results indicate that long-term exposure to low doses of UVB induces immunomodulation in fish, and that there are species-specific differences in sensitivity to irradiation.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2009-01-24 | Photochemistry and photobiology |