6533b7d6fe1ef96bd12664de
RESEARCH PRODUCT
Imidazolsynthesen, 8. Mitt.: N-Substituierte Imidazole nach Weidenhagen
Walter SchunackVolker Stoecksubject
Ammoniachemistry.chemical_compoundAqueous solutionchemistryDrug DiscoveryOxidizing agentPharmaceutical ScienceOrganic chemistrychemistry.chemical_elementImidazoleAmine gas treatingMedicinal chemistryCopperdescription
Die Weidenhagen-Synthese N-unsubstituierter Imidazole aus α-substituierten Carbonylverbindungen 1, Aldehyden 3, wasrigem Ammoniak (4) und Kupfer(II)-salzen als Oxidationsmittel ist in Gegenwart primarer Amine 5 auch zur Darstellung N-substituierter Imidazole 6 geeignet. Weidenhagen Synthesis of N-Substituted Imidazoles The Weidenhagen synthesis of N-unsubstituted imidazoles from α-substituted carbonyl compounds 1, aldehydes 3, and aqueous ammonia (4) with copper (II) salts as oxidizing agents is also usable for the synthesis of N-substituted imidazoles 6 through the addition of primary amines 5.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1976-01-01 | Archiv der Pharmazie |