6533b7d6fe1ef96bd126674f

RESEARCH PRODUCT

Colourimetric image analysis as a diagnostic tool in female genital schistosomiasis

Sigve HolmenSigve HolmenSvein Gunnar GundersenElisabeth KleppaElisabeth KleppaMyra TaylorMathias OnsrudEyrun Floerecke KjetlandKristine LillebøFritz Albregtsen

subject

Female circumcisionmedicine.medical_specialtyAdolescent030231 tropical medicineBiophysicsBiomedical EngineeringSchistosomiasisReproductive Tract Infections03 medical and health sciencesYoung Adult0302 clinical medicinemedicineImage Processing Computer-AssistedHumansSchistosomiasis030212 general & internal medicineDiagnosis Computer-AssistedGynecologyColposcopymedicine.diagnostic_testbusiness.industryWaterborne diseasesmedicine.disease3. Good healthROC CurveClinical diagnosisColorimetryFemaleRadiologybusinessCell Phone

description

Female genital schistosomiasis (FGS) is a highly prevalent waterborne disease in some of the poorest areas of sub-Saharan Africa. Reliable and affordable diagnostics are unavailable. We explored colourimetric image analysis to identify the characteristic, yellow lesions caused by FGS. We found that the method may yield a sensitivity of 83% and a specificity of 73% in colposcopic images. The accuracy was also explored in images of simulated inferior quality, to assess the possibility of implementing such a method in simple, electronic devices. This represents the first step towards developing a safe and affordable aid in clinical diagnosis, allowing for a point-of-care approach.

10.1016/j.medengphy.2014.12.007http://dx.doi.org/10.1016/j.medengphy.2014.12.007