6533b7d6fe1ef96bd1266e41
RESEARCH PRODUCT
Individualized Tumor Therapy: Biomarkers and Possibilities for Targeted Therapy with Natural Products
Thomas EfferthThomas Efferthsubject
Oncologymedicine.medical_specialtyChemotherapybiologybusiness.industrymedicine.medical_treatmentTumor therapyCancerContext (language use)Synthetic lethalitymedicine.diseasePredictive valueTargeted therapyInternal medicinemedicinebiology.proteinEpidermal growth factor receptorbusinessdescription
Although many tumors respond to chemotherapy, not all patients benefit from anticancer drugs. Tumors often develop resistance to drugs and concentrations sufficient to eradicate the cancer cannot be used due to the severe side effects of chemotherapy. In the present chapter, we give an overview of research on biomarkers with prognostic and predictive value and summarize our own efforts in this context. With a battery of biomarkers and corresponding synthetic and natural targeted drugs, it is likely that custom-tailored combination treatments will soon become a reality and that each individual cancer patient will be treated based on his or her individual molecular tumor architecture.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2014-01-01 |