6533b7d6fe1ef96bd1267244

RESEARCH PRODUCT

Occupational sun exposure and mycosis fungoides: a European multicenter case-control study.

Preben JohansenFranco MerlettiPatrick ArveuxWolfgang AhrensJørn OlsenMaría Morales-suárez-varelaGun WingrenLennart HardellGiovanna MasalaFrancisco Guillén-grimaLinda KaerlevAgustin LlopisPascal GuénelAndreas Stang

subject

MaleMESH: Occupational Exposure030207 dermatology & venereal diseases0302 clinical medicineRisk FactorsMESH: Risk FactorsEpidemiologyOdds RatioMESH: Agededucation.field_of_studyMESH: Middle AgedPigmentationMiddle AgedMESH: Case-Control StudiesCausalityEuropeOccupational Diseases030220 oncology & carcinogenesisSunlightFemaleMESH: Occupational Diseasesmedicine.medical_specialtyMESH: SunlightPopulationJob-exposure matrixMESH: CausalityMESH: PigmentationOccupational medicine03 medical and health sciencesMycosis FungoidesOccupational ExposuremedicineHumanseducationAgedMycosis fungoidesMESH: Humansbusiness.industryMESH: Mycosis FungoidesPublic Health Environmental and Occupational HealthCase-control studyOdds ratiomedicine.diseaseDermatologyConfidence intervalMESH: Odds RatioMESH: MaleSurgery[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologieCase-Control Studies[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieMESH: EuropebusinessMESH: Female

description

International audience; OBJECTIVE: We sought to study the association between occupational sun exposure and mycosis fungoides (MF), a peripheral T-cell lymphoma. SUBJECTS AND METHODS: A European multicenter case-control study including seven rare cases (one being MF) was conducted between 1995 and 1997. From the 118 accepted cases, 104 were interviewed, of which 76 were definite cases. Population controls were selected randomly from the regions of case ascertainment. Information based on occupational experiences was coded according to industry types. A job exposure matrix was created according to the expected exposure to sunlight. RESULTS: Once exposures to aromatic halogenated hydrocarbons were eliminated (odds ratio = 2.3; 95% confidence interval = 0.9-6.2), a high MF risk was associated with exposures to solar radiation. CONCLUSION: It would appear that workers exposed to sunlight have a higher risk of MF. However, this factor is not the only one involved.

10.1097/01.jom.0000194160.95468.20https://www.hal.inserm.fr/inserm-00257244