6533b7d7fe1ef96bd12678d8

RESEARCH PRODUCT

Herbizide, 1. Mitt. 2-(4-Nitroanilino)pyrimidine

B. RichterAlfred Kreutzberger

subject

chemistry.chemical_compoundPyrimidineChemistryStereochemistryDrug DiscoveryPharmaceutical Science

description

Aus der Kondensation von 4-Nitrophenylguanidin (1) mit den β-Diketonen 2a–h gehen die 2-(4-Nitroanilino)pyrimidine 3a–h hervor. Als Aminoheterocyclus steht Verbindungstyp 3 in enger struktureller Beziehung zu 5-Acetyl-2-amino-4-methylthiazol, das herbizide Wirkungen auszuuben vermag. Herbicides, I: 2-(4-Nitroanilino)pyrimidines Condensation of 4-nitrophenylguanidine (1) with the β-diketones 2a–h yields the 2-(4-nitroanilino)pyrimidines 3a–h. Compounds of type 3 are aminoheterocycles and as such are closely related to 5-acetyl-2-amino-4-methylthiazole which exhibits herbicidal activity.

https://doi.org/10.1002/ardp.19823150103