6533b7d7fe1ef96bd12679d9
RESEARCH PRODUCT
Tissue optical perfusion pressure: a simplified, more reliable, and faster assessment of pedal microcirculation in peripheral artery disease
Gerhard WeisserLaura MessnerGeorg HorstickAnna GrundmannChristine Espinola-kleinSenay Yalcinsubject
Malemedicine.medical_specialtyPhysiologyArterial diseaseBlood Pressure030204 cardiovascular system & hematologyWorkflowMicrocirculationPeripheral Arterial Disease03 medical and health sciences0302 clinical medicinePredictive Value of TestsOscillometryPhysiology (medical)Internal medicinePhotoplethysmogramHumansMedicineAnkle Brachial Index030212 general & internal medicinePhotoplethysmographyAgedRetrospective StudiesAged 80 and overFootbusiness.industryMicrocirculationReproducibility of ResultsUltrasonography DopplerMiddle Agedbody regionsRegional Blood FlowCardiologyFemaleCardiology and Cardiovascular MedicinebusinessPerfusiondescription
Oscillometry is an alternative to continuous-wave Doppler (cw-Doppler) to determine peripheral artery disease (PAD) severity using the ankle-brachial index (ABI). cw-Doppler ABI differentiates systolic pressure of ATP and ADP where either one of both values in most patients is higher (high) and the other value is lower (low). In contrast, oscillometric ABI measures the strongest signal and hence misses the lower value. Both do not take pedal perfusion into consideration. Simultaneous determination of tissue microperfusion cares for pedal PAD. ABI was determined by cw-Doppler and oscillometry. Tissue optical perfusion pressure (TOPP) was taken from the first toe using photoplethysmography. 323 patients were evaluated retrospectively in 3 independent groups.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-09-19 | American Journal of Physiology-Heart and Circulatory Physiology |