6533b7d7fe1ef96bd126909a

RESEARCH PRODUCT

EDSS correlated analysis of median nerve somatosensory evoked potentials in multiple sclerosis

J. KoehlerA. FaldumH.c. Hopf

subject

AdultMalemedicine.medical_specialtyMultiple SclerosisNeurologyNeural ConductionDermatologyAudiologyEvoked Potentials SomatosensoryInternal medicinemedicineHumansAgedNeuroradiologyExpanded Disability Status ScaleMultiple sclerosisBrainGeneral MedicineMiddle Agedmedicine.diseaseMedian nerveMedian NervePeripheralPsychiatry and Mental healthSomatosensory evoked potentialCardiologyFemaleNeurology (clinical)NeurosurgeryPsychology

description

Median nerve somatosensory evoked potentials (SEP) were recorded in 30 patients with multiple sclerosis. The examined patients had an expanded disability status scale (EDSS) between 0 and 6. The primary cortical potential N20, the subcortical potentials P14, N13b, N13a and the peripheral potential P9 were recorded simultaneously. In 5 patients normal SEP were observed (group 1), and in 6 patients there were consecutive disturbances of the somatosensory pathway (group 3). In 19 patients subcortical potentials were abnormal or absent while the following potentials were normal or identified which pattern corresponds to amplification within CNS structures (group 2). The EDSS of groups 1 and 2 were similar and lower than the EDSS of group 3, which indicates that amplification mechanisms could represent a positive prognostic factor in SEP diagnosis of multiple sclerosis.

yearjournalcountryeditionlanguage
2001-02-24Neurological Sciences
https://doi.org/10.1007/s100720070079