6533b7d8fe1ef96bd12696bb

RESEARCH PRODUCT

ChemInform Abstract: α-Cyanation of Aromatic Tertiary Amines Using Ferricyanide as a Non-Toxic Cyanide Source.

Alexander M. NauthTill OpatzNicola Otto

subject

chemistry.chemical_classificationchemistry.chemical_compoundchemistryCyanideOrganic chemistrychemistry.chemical_elementGeneral MedicineFerricyanideIsoquinolineCyanationNitrogenAmino acid

description

Aromatic tertiary amines, mostly isoquinoline derivatives and analogous N-heterocycles, are treated with the non-toxic agent (II) under conditions A) or B) to produce the desired N-aminonitrile compounds as amino acid precursors and as building blocks of complex nitrogen heterocycles.

https://doi.org/10.1002/chin.201615050