6533b7d8fe1ef96bd12697a5
RESEARCH PRODUCT
Über eine mangelnde Parallelität zwischen Ionenpumpenhemmung und Kontraktionskraftsteigerung
G. KuschinskyUwe WollertH. Lüllmannsubject
PharmacologyCellular and Molecular NeuroscienceChemistryStereochemistryMolecular MedicineIonic bondingCell BiologyMolecular BiologyMechanism (sociology)description
Δ 5-Pregnen-3,20-dione-N,N'-ethylpyrrolidine-bisguanylhydrazone and Δ5-pregnen-3β-hydroxy-20-one-N,N'-ethyl-pyrrolidine-monoguanylhydrazone inhibit the activity of the ionic pump of cold-stored erythrocytes of guinea-pigs. The contractile force of isolated guinea-pig auricles is decreased by the mono-derivate and increased by the bis-derivate in spite of the similar action upon the pumping mechanism.
year | journal | country | edition | language |
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1964-10-01 | Experientia |