6533b7d8fe1ef96bd126a1e2

RESEARCH PRODUCT

Elimination of Parathion by Hemoperfusion in Severe E 605 ForteR Intoxication in Vivo

S. Okonek

subject

biologymedicine.drug_classmedicine.medical_treatmentHalothane anaesthesiamacromolecular substancesPharmacologyHemoperfusionchemistry.chemical_compoundParathionchemistryIn vivobiology.proteinmedicineCarbonic anhydrase inhibitorAcetylcholineCholinesterasemedicine.drug

description

Severe parathion (P) intoxication results in complete inhibition of cholinesterase activity and toxic accumulation of acetylcholine. Besides these well known biochemical changes, there is evidence of direct toxic effects on the cardio-vascular system which may prove fatal due to an excess of P.

https://doi.org/10.1007/978-3-662-39532-5_264