6533b7d8fe1ef96bd126a38a

RESEARCH PRODUCT

Presence of atrial natriuretic factor in normal and hyperplastic human prostate and its relationship with oxytocin localisation

E. Farina-lipariRita AnzaloneBiagio ValentinoFrancesco CappelloMarianna BellafioreLipari D

subject

MaleProstatic Diseasesmedicine.medical_specialtyHistologyStromal cellProstatic HyperplasiaBiophysicsProstatic hyperplasia pathogenesiOxytocinHuman prostateImmunoenzyme TechniquesParacrine signallingProstatic fluidInternal medicineotorhinolaryngologic diseasesmedicineHumanslcsh:QH301-705.5ANF; Oxytocin; Prostatic fluid; Prostatic hyperplasia pathogenesis; Cell Biology; Anatomy; Animal Science and Zoology; Developmental Biologybusiness.industryProstateCell BiologyHyperplasiamusculoskeletal systemmedicine.diseaseEndocrinologylcsh:Biology (General)OxytocinANFembryonic structurescardiovascular systemAnimal Science and ZoologyAnatomyStromal CellsbusinessAtrial Natriuretic Factorhormones hormone substitutes and hormone antagonistsDevelopmental Biologymedicine.drugHormone

description

In this work, we showed the presence of atrial natriuretic factor (ANF) in human prostate and compared its localisation in normal and hyperplastic conditions. ANF was localised in epithelial and stromal cells, being increased in hyperplasia, mainly in the stromal component. Moreover, we compared ANF and oxytocin positivity in the same glands, focusing on the possible relationship between the paracrine effects of these two hormones.

yearjournalcountryeditionlanguage
2003-01-01European Journal of Histochemistry
https://doi.org/10.4081/818