6533b7d8fe1ef96bd126a4b8
RESEARCH PRODUCT
Neoclerodanes from Teucrium orientale
Maurizio BrunoSergio RosselliAntonella MaggioNelly A. ArnoldLeonardo ScaglioniFranco PiozziMonique S. J. Simmondssubject
LamiaceaeMagnetic Resonance SpectroscopyLamiaceae Teucrium orientale structure elucidation neo-clerodane diterpenoid antifeedant activityTraditional medicinebiologyStereochemistryChemistryMolecular ConformationTeucrium oliverianumGeneral ChemistryFeeding BehaviorGeneral MedicineSettore CHIM/06 - Chimica OrganicaSpodopterabiology.organism_classificationDiterpenes ClerodaneTerpeneLarvaDrug DiscoveryTeucrium orientaleAnimalsLamiaceaeChromatography Thin LayerSettore BIO/15 - Biologia FarmaceuticaSpodoptera littoralisdescription
Abstract Two new neoclerodane diterpenoids, 6-deacetyl-teucrolivin A (5) and 8beta-hydroxy-teucrolivin B (6), were isolated from the aerial parts of Teucrium orientale, along with four already known neoclerodane diterpenoids, teucrolivin A (1), teucrolivin B (2), teucrolivin C (3) and teucrolivin H (4), previously isolated from Teucrium oliverianum. Their structures were elucidated on the basis of spectroscopic evidence and chemical transformations. Compounds 1-3 were assayed for antifeedant activity against Spodoptera littoralis, S. frugiperda and Heliocoverpa armigera. Teucrolivin A was the most potent of the three compounds tested.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2004-01-01 |