0000000000230146

AUTHOR

Nelly A. Arnold

showing 2 related works from this author

Guaianolides from the Aerial Parts of Centaurea Hololeuca

2006

Seven guaianolides were isolated from the acetone extract of the aerial parts of Centaurea hololeuca Boiss. The antifeedant activity of the natural compounds (1–7) and of four chloro derivatives (8–11), synthesized from repin (1) and janerin (3) were tested against larvae of Spodoptera littoralis. Cebellin J (6) and chlorojanerin (11) showed significant antifeedant activity at 100 ppm, whereas at this concentration cebellin G (4) and 15-deschloro-15-hydroxychlorojanerin (7) stimulated feeding. Cebellin G (4) stimulated larvae of S. littoralis to feed at low concentration, but deterred feeding at high concentrations. The addition of chlorine to repin (1) resulted in an increase in antifeeda…

0106 biological sciencesPharmacologybiologyChemistryPlant ScienceGeneral Medicinebiology.organism_classification010603 evolutionary biology01 natural sciencesComplementary and alternative medicineCentaureaDrug DiscoveryBotany010606 plant biology & botanyNatural Product Communications
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Neoclerodanes from Teucrium orientale

2004

Abstract Two new neoclerodane diterpenoids, 6-deacetyl-teucrolivin A (5) and 8beta-hydroxy-teucrolivin B (6), were isolated from the aerial parts of Teucrium orientale, along with four already known neoclerodane diterpenoids, teucrolivin A (1), teucrolivin B (2), teucrolivin C (3) and teucrolivin H (4), previously isolated from Teucrium oliverianum. Their structures were elucidated on the basis of spectroscopic evidence and chemical transformations. Compounds 1-3 were assayed for antifeedant activity against Spodoptera littoralis, S. frugiperda and Heliocoverpa armigera. Teucrolivin A was the most potent of the three compounds tested.

LamiaceaeMagnetic Resonance SpectroscopyLamiaceae Teucrium orientale structure elucidation neo-clerodane diterpenoid antifeedant activityTraditional medicinebiologyStereochemistryChemistryMolecular ConformationTeucrium oliverianumGeneral ChemistryFeeding BehaviorGeneral MedicineSettore CHIM/06 - Chimica OrganicaSpodopterabiology.organism_classificationDiterpenes ClerodaneTerpeneLarvaDrug DiscoveryTeucrium orientaleAnimalsLamiaceaeChromatography Thin LayerSettore BIO/15 - Biologia FarmaceuticaSpodoptera littoralis
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