6533b7d8fe1ef96bd126ab99
RESEARCH PRODUCT
Enzephalopathie nach Intoxikation mit einem Anticholinergikum
Maier WA. MuttrayDemuth WVogt TKonietzko Jsubject
medicine.drug_classbusiness.industryToxic encephalopathyAcute intoxicationOcular hypertensionGeneral MedicineChemical laboratoryTest agentmedicine.diseaseAnesthesiamedicineAnticholinergicMydriasisDeliriummedicine.symptombusinessdescription
A 55-year-old chemical laboratory technician developed mydriasis and ocular hypertension, which lasted for 6 weeks, after synthesizing several kilograms of a scopolamine-related test agent with anticholinergic action and then decanting a powdery intermediary substance, the dust of which he may have inhaled. Six weeks later he suddenly had symptoms of an acute intoxication while synthesizing a scopolamine-related substance. The anticholinergic delirium regressed completely within one day requiring no treatment. But subsequently he developed symptoms of a toxic encephalopathy. This only partially regressed over the following 3 years. Its probable cause is thought to have been either the manifestation of an already existing organic cerebral psychiatric syndrome or an as yet unknown effect of the test substance.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2008-03-25 | DMW - Deutsche Medizinische Wochenschrift |