6533b7d8fe1ef96bd126ad5c
RESEARCH PRODUCT
A feline rotavirus G3P[9] carries traces of multiple reassortment events and resembles rare human G3P[9] rotaviruses.
Canio BuonavogliaNicola DecaroVito MartellaKrisztián BányaiA. C. PotgieterEleonora LorussoGiovanni M. GiammancoAntonio LavazzaJelle MatthijnssensS. De GraziaMax Ciarletsubject
RotavirusSettore MED/07 - Microbiologia E Microbiologia ClinicaSequence analysisReassortmentMolecular Sequence DataReoviridaeSequence HomologyBiologymedicine.disease_causeGenomeG3PhylogeneticsVirologyRotavirusmedicineAnimalsCluster AnalysisHumansfelinePhylogenyGeneticsWhole genome sequencingPhylogenetic treeSequence Analysis DNARotavirubiology.organism_classificationVirologyP[9]reassortantCatsRNA ViralReassortant Virusesdescription
The full-length genome sequence of a feline G3P[9] rotavirus (RV) strain, BA222, identified from the intestinal content of an adult cat, was determined. Strain BA222 possessed a G3-P[9]-I2-R2-C2-M2-A3-N1-T3-E2-H3 genomic constellation, differing substantially from other feline RVs. Phylogenetic analyses of each genome segment revealed common origins with selected animal and zoonotic human RVs, notably with rare multi-reassortant human G3P[9] RVs (Ita/PAI58/96 and Ita/PAH136/96). Altogether, the findings suggest that feline RVs are genetically diverse and that human RVs may occasionally originate either directly or indirectly (via reassortment) from feline RVs.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2011-05-01 | The Journal of general virology |