6533b7d8fe1ef96bd126b6c1

RESEARCH PRODUCT

Monitoring of Chemically Induced Colitis

Sonja ReißigBenno Weigmann

subject

0301 basic medicinebusiness.industryInflammationDiseasemedicine.diseaseInflammatory bowel diseaseChemically-induced colitisUlcerative colitisdigestive system diseasesPathogenesis03 medical and health sciences030104 developmental biologyMucosal immunologyImmunologymedicineColitismedicine.symptombusiness

description

Inflammation is a common symptom of inflammatory bowel disease (IBD). Actually, many experimental models of colitis exist and try to mimic the human situation in order to understand the pathogenesis of Crohn's disease and ulcerative colitis. These experimental models of inflammation can be characterized by specific parameters, which illustrate the proceeding inflammatory process. By use of these models potentially new reagents for improved therapeutic approaches can be analyzed. Here, we describe the TNBS-mediated colitis model and specify different parameters for the detailed characterization of the inflammatory process in experimental colitis models.

yearjournalcountryeditionlanguage
2017-01-01
https://doi.org/10.1007/978-1-4939-6786-5_20