6533b7d9fe1ef96bd126b9c9

RESEARCH PRODUCT

Tumor Volume, CT Scan, Lymphography, Sonography, Intravenous Pyelography, and Tumor Markers in Testis Tumors

Peter AlkenR. HohenfellnerGünther H. JacobiDirk M. WilbertKlose Kj

subject

AdultMalemedicine.medical_specialtyUrologyTesticular tumorComputed tomographyChorionic GonadotropinTesticular NeoplasmsTestis tumorsTestisTumor stageIntravenous PyelogramBiomarkers TumorHumansMedicineChorionic Gonadotropin beta Subunit HumanTumor LoadNeoplasm StagingUltrasonographymedicine.diagnostic_testbusiness.industryLymphographyUrographyIntravenous pyelographyNeoplasms Germ Cell and EmbryonalPeptide Fragmentsalpha-FetoproteinsRadiologyTomography X-Ray Computedbusiness

description

Correlation of tumor volume to tumor stage in 134 patients with nonseminomatous testicular tumors, which were classified according to the TNM system, revealed similar tumor load for N0 and N1 patients. CT scans (n = 92), lymphangiography (n = 47), intravenous pyelography (IVP) (n = 134), sonography (n = 118) and serial tumor markers (n = 82) were evaluated for sensitivity, specificity and accuracy, both separately and in different combinations. The best individual results were obtained by lymphangiography (sensitivity 0.77, specificity 0.73, accuracy 0.75) and CT scan (sensitivity 0.52, specificity 0.91, accuracy 0.70). In combination CT scan and lymphangiography were the most valuable diagnostic tools (accuracy 0.79) with high sensitivity (0.88) and specificity (0.77). For patients with negative CT scans, subsequent lymphangiography is recommended for accurate staging, as seems mandatory in stage 1 patients entering surveillance programs.

yearjournalcountryeditionlanguage
1989-01-01Urologia Internationalis
https://doi.org/10.1159/000281442