6533b7d9fe1ef96bd126bfd7

RESEARCH PRODUCT

Application of DNA Polymorphisms in Paternity Testing in Germany: Solution of an Incest Case Using Bacteriophage M13 Hybridization with Hypervariable Minisatellite DNA

G. RittnerPeter M. SchneiderU. SchackerCh. Rittner

subject

GeneticsBacteriophageMinisatelliteOffspringMutation (genetic algorithm)Dna polymorphismBiologybiology.organism_classification

description

More than 25 blood, serum, and enzyme polymorphisms have been introduced into paternity testing in Germany in recent years (Rittner, 1975). If a “no” decision is defined by exclusion, and a “yes” decision requires a probability of 99.73 % or more, more than 90 % of court cases can be solved in this respect. A few cases not being clarified by a standard expertise include: 1) Cases with more than one alleged man if the men and/or the mother and the men are related. 2) Some cases where the putative father is deceased, and neither the parents nor the legitimate offspring are available for the study. 3) Cases where possible exclusion in a given polymorphic system interferes with an overall evidence in favor of paternity of the alleged man. The “exclusion” could then be traced back to a mutation.

https://doi.org/10.1007/978-3-642-73330-7_75