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RESEARCH PRODUCT
Tips on ligand immobilization and kinetic study using surface plasmon resonance.
Jafar Ezzati Nazhad DolatabadiMiguel De La Guardiasubject
AnalyteStereochemistryKineticseducationPharmaceutical Science02 engineering and technology01 natural sciencesGeneral Biochemistry Genetics and Molecular BiologyAnalyteAdsorptionNucleotidaseSurface plasmon resonanceSurface plasmon resonancelcsh:QH301-705.5Ligand immobilizationlcsh:R5-920Chemistry010401 analytical chemistryGeneral Medicine021001 nanoscience & nanotechnologyLigand (biochemistry)Small moleculeCombinatorial chemistry0104 chemical sciencesKinetic studyEditoriallcsh:Biology (General)0210 nano-technologylcsh:Medicine (General)Macromoleculedescription
Surface plasmon resonance (SPR) technique offers a robust label-free approach applicable in various investigations including binding affinity, specificity and kinetics of biological macromolecules (e.g., peptides, proteins and nucleotidase) and small molecules. SPR provides extremely important data on the kinetics and affinity of substances examined, through which bio-specific interaction(s) can be established by the analysis of adsorption of analyte onto the immobilized ligand(s) on a sensor-based analytical system. Due to SPR wide applications in biomedical laboratories, the aim of this editorial is to highlight the importance of SPR in affinity kinetics and ligand immobilization.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-08-30 | BioImpacts : BI |