6533b7d9fe1ef96bd126d7c7

RESEARCH PRODUCT

Determination of sialic acid and gangliosides in biological samples and dairy products: A review

Ramón LacombaAmparo AlegríaReyes BarberáEsther MatencioM. Jesús LagardaJaime Salcedo

subject

ChromatographyGangliosideChromatographySpectrum AnalysisClinical BiochemistryPharmaceutical ScienceSphingolipidN-Acetylneuraminic AcidAnalytical ChemistrySialic acidcarbohydrates (lipids)chemistry.chemical_compoundGlycolipidBiochemistrychemistryMilk productsGangliosidesDrug DiscoveryAnimalsDairy ProductsQuantitative analysis (chemistry)Spectroscopy

description

Gangliosides are sphingolipids containing one or more moieties of sialic acid in their structure. Both gangliosides and sialic acid are bioactive compounds related to animal physiology. Due to their biological relevance, analytical methods adapted to each type of matrix have been developed over time. The present study reviews the main methods applied to the analysis of sialic acid and gangliosides in biological samples and dairy products.

https://doi.org/10.1016/j.jpba.2009.04.023