6533b7dafe1ef96bd126e130
RESEARCH PRODUCT
Towards noncontact skin melanoma selection by multispectral imaging analysis
Lauma ValeineIlona KuzminaJanis SpigulisJanis KapostinshDainis JakovelsIlze DiebeleAnna Berzinasubject
Diagnostic ImagingMalePathologymedicine.medical_specialtyMultispectral imageBiomedical EngineeringSkin PigmentationOptical densityBiomaterialsLesionHemoglobinsImage Processing Computer-AssistedHumansMedicineMelanomaSkinMelaninsbusiness.industrySpectrum AnalysisMelanomamedicine.diseaseAtomic and Molecular Physics and OpticsElectronic Optical and Magnetic MaterialsOxyhemoglobinsFemalesense organsmedicine.symptomSkin melanomabusinessSkin lesionSoftwareBiomedical engineeringdescription
A clinical trial comprising 334 pigmented and vascular lesions has been performed in three Riga clinics by means of multispectral imaging analysis. The imaging system Nuance 2.4 (CRi) and self-developed software for mapping of the main skin chromophores were used. Spe- cific features were observed and analyzed for malignant skin melanomas: notably higher absorbance (especially as the difference of optical density relative to the healthy skin), uneven chromophore distribution over the lesion area, and the possibility to select the "melanoma areas" in the correla- tion graphs of chromophores. The obtained results indicate clinical potential of this technology for noncontact selec- tion of melanoma from other pigmented and vascular skin lesions. C 2011 Society of Photo-Optical Instrumentation Engineers (SPIE).
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2011-07-05 | Journal of Biomedical Optics |