6533b7dbfe1ef96bd126f80f

RESEARCH PRODUCT

Cardiovascular imaging in the diagnosis and monitoring of cardiotoxicity: Role of echocardiography

Concetta ZitoDonato MeleSonia Dell’oglioAlessia PepeLuca LongobardoCarlo G. TocchettiInes MonteGiuseppina NovoChristian CadedduRosalinda Madonna

subject

Cardiac function curvemedicine.medical_specialtymedicine.medical_treatmentLeftEchocardiography Three-DimensionalcardiotoxicityAntineoplastic Agents030204 cardiovascular system & hematologychemotherapycancer cardiotoxicity chemotherapy echocardiographyVentricular Function Left03 medical and health sciences0302 clinical medicineInternal medicineNeoplasmsmedicinecancerHumansVentricular FunctionHeart FailureCardiotoxicityChemotherapyVentricular functionbusiness.industryCancerHeartGeneral Medicinemedicine.diseaseEchocardiography Doppler Colorcancer; cardiotoxicity; chemotherapy; echocardiography; Antineoplastic Agents; Cardiotoxicity; Heart; Heart Failure; Humans; Neoplasms; Ventricular Function Left; Early Diagnosis; Echocardiography Three-Dimensionalcancer; cardiotoxicity; echocardiographyEarly DiagnosisCardiovascular DiseasesEchocardiography030220 oncology & carcinogenesisHeart failureThree-DimensionalCardiologyCardiology and Cardiovascular Medicinebusiness

description

The evaluation by cardiovascular imaging of chemotherapy patients became a central topic in the last several years. The use of drugs for the treatment of cancers increased, and new molecules and protocols were developed to improve outcomes in these patients. Although, these novel approaches also produced a progressive increase in side effects, particularly myocardial dysfunction. Imaging of the heart was highly accurate in the early diagnosis of cancer therapeutics related-cardiac dysfunction. Echocardiography is the first-line method to assess ventricular function alterations, and it is required to satisfy the need for an early, easy and accurate diagnosis to stratify the risk of heart failure and manage treatments. A careful monitoring of cardiac function during the course of therapy should prevent the onset of severe heart impairment. This review provides an overview of the most important findings of the role of echocardiography in the management of chemotherapy-treated patients to create a clear and complete description of the efficacy of conventional measurements, the importance of comprehensive heart evaluations, the additional role of new echocardiographic techniques, the utility of integrated studies using other imaging tools and the positions of the most important international societies on this topic.

10.2459/jcm.0000000000000374http://hdl.handle.net/11568/1021953