6533b7dbfe1ef96bd126fead
RESEARCH PRODUCT
Die Wirkung von Thiopental-Natrium und Pentobarbital-Natrium auf die Nierengef��e von M�usen
H. VorherrB. CullmannP. JungblutG. Kuschinskysubject
PharmacologyLong lastingKidneyPentobarbitalNarcoticbusiness.industrymedicine.medical_treatmentPharmacology toxicologyGeneral MedicineVascular tonemedicine.anatomical_structureBlood pressureAnesthesiaCortex (anatomy)medicinebusinessmedicine.drugdescription
The action of intravenous injections of pentobarbital and of thiopental on the blood pressure and on the vascular tone in the cortex of the kidney has been studied in albino mice. Pentobarbital caused a pronounced decrease of the filling of blood vessels in the cortex of kidneys together with a long-lasting anaesthesia and a long lasting fall of blood pressure. Thiopental, on the other hand, was less effective on the filling of blood vessels, while its narcotic effect was small and the fall of blood pressure less pronounced. The results indicate that both substances increased the vascular tone in the cortex of the kidney.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1957-01-01 | Naunyn-Schmiedebergs Archiv f�r Experimentelle Pathologie und Pharmakologie |