6533b7dbfe1ef96bd1270ab1
RESEARCH PRODUCT
Treatment challenges in and outside a network setting: Head and neck cancers.
Ester OrlandiSalvatore AlfieriChristian SimonAnnalisa TramaLisa LicitraMonika HacklElizabeth Van EyckenKris HenauNadya DimitrovaMario SekerijaLadislav DušekMargit MägiNea MalilaMaarit LeinonenMichel VeltenXavier TroussardVeronique BouvierAnne-valérie GuizardAnne-marie BouvierPatrick ArveuxMarc MaynadiéAnne-sophie WoronoffMichel RobaszkiewicIsabelle BaldiAlain MonnereauBrigitte TretarreMarc ColonnaFlorence MoliniéSimona BaraClaire SchvartzBénédicte Lapôtre-ledouxPascale GrosclaudeRoland StabenowSabine LuttmannAlice NenneckeJutta EngelGabriele Schubert-fritschleJan HeidrichBernd HolleczekJón Gunnlaugur JónassonKerri Clough-gorrHarry ComberGuido MazzoleniAdriano GiacominAntonella Sutera SardoAlessandr BarchielliDiego SerrainoRoberta De AngelisSandra MalloneAndrea TavillaDaniela PierannunzioSilvia RossiMariano SantaquilaniArnold KnijnFabio PannozzoValerio GennaroLucia BenfattoPaolo RicciMariangela AutelitanoGianbattista SpagnoliMario FuscoMario UsalaVitale FrancescoMaria MichiaraRosario TuminoLucia MangoneFabio FalciniStefano FerrettiRosa Angela FilibertiEnza MaraniArturo IannelliFlavio SensiSilvano PifferMaria GentiliniAnselmo MadedduAntonio ZiinoSergio MasperoPina CandelaFabrizio StracciGiovanna TagliabueMassimo RuggeAnnalisa TramaGemma GattaLaura BottaRiccardo CapocacciaSanta PildavaGiedre SmailyteNeville CallejaTom Børge JohannesenJadwiga RachtanStanisław GóźdźJerzy BłaszczykKamila KępskaGonçalo Forjaz De LacerdaMaria José BentoAna MirandaChakameh Safaei DibaEnrique AlmarNerea LarrañagaArantza Lopez De MunainAna Torrella-ramosJosé María Díaz GarcíaRafael Marcos-grageraMaria Josè SanchezCarmen NavarroDiego SalmeronConchi Moreno-iribasJaume GalceranMarià CarullaMohsen MousaviChristine BouchardySilvia M. EssAndrea BordoniIsabelle KonzelmannJem RashbassAnna GavinDavid BrewsterDyfed Wyn HuwsOtto VisserMagdalena Bielska-lasotaMaja Primic-zakeljIan KunklerEllen Benhamousubject
0301 basic medicinemedicine.medical_specialtySocio-culturaleSocial issuesMultidisciplinary team03 medical and health sciencesTherapeutic approach0302 clinical medicineRare DiseasesMultidisciplinary approachmedicineHumansAdverse effectIntensive care medicineHead and neck cancerReferral and ConsultationPatient Care TeamEuropean reference networks joint action of rare cancers ; Head and neck cancer ; Multidisciplinary team ; Rare diseasebusiness.industryHead and Neck NeoplasmHead and neck cancerEuropean reference networks joint action of rare cancersGeneral MedicineMultidisciplinary teammedicine.diseaseEurope030104 developmental biologyClinical researchOncologyHead and Neck Neoplasms030220 oncology & carcinogenesisEuropean reference networks joint action of rare cancerSurgerybusinessEuropean reference networks joint action of rare cancers; Head and neck cancer; Multidisciplinary team; Rare disease; Surgery; OncologyRare diseaseDelivery of Health CareRare diseaseHumandescription
Head and neck cancer (HNC) is a rare disease that can affect different sites and is characterized by variable incidence and 5-year survival rates across Europe. Multiple factors need to be considered when choosing the most appropriate treatment for HNC patients, such as age, comorbidities, social issues, and especially whether to prefer surgery or radiation-based protocols. Given the complexity of this scenario, the creation of a highly specialized multidisciplinary team is recommended to guarantee the best oncological outcome and prevent or adequately treat any adverse effect. Data from literature suggest that the multidisciplinary team-based approach is beneficial for HNC patients and lead to improved survival rates. This result is likely due to improved diagnostic and staging accuracy, a more efficacious therapeutic approach and enhanced communication across disciplines. Despite the benefit of MTD, it must be noted that this approach requires considerable time, effort and financial resources and is usually more frequent in highly organized and high-volume centers. Literature data on clinical research suggest that patients treated in high-accrual centers report better treatment outcomes compared to patients treated in low-volume centers, where a lower radiotherapy-compliance and worst overall survival have been reported. There is general agreement that treatment of rare cancers such as HNC should be concentrated in high volume, specialized and multidisciplinary centers. In order to achieve this goal, the creation of international collaboration network is fundamental. The European Reference Networks for example aim to create an international virtual advisory board, whose objectives are the exchange of expertise, training, clinical collaboration and the reduction of disparities and enhancement of rationalize migration across Europe. The purpose of our work is to review all aspects and challenges in and outside this network setting planned for the management of HNC patients.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2019-01-01 | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology |