6533b7dbfe1ef96bd1270c3e

RESEARCH PRODUCT

Lethal systemic and brain infection caused by Prototheca zopfii algae in a patient with acute myeloid leukemia

Ekkehard SiegelDaniela ToelleMarkus MunderJoachim KaesStephanie HeroldTristan KlodtMartin DennebaumDaniel TeschnerAndreas KreftElena LippeCleo Walz

subject

0301 basic medicineProtothecosisMedicine (General)QH301-705.5medicine.medical_treatmentProtothecosis030106 microbiology030231 tropical medicinePrototheca zopfiiCase ReportMicrobiologySepsis03 medical and health sciences0302 clinical medicineR5-920medicineImmunodeficiencyBiology (General)ImmunodeficiencyChemotherapyLeukemiabusiness.industrySeptic shockMyeloid leukemiamedicine.diseaseLeukemiaInfectious DiseasesImmunologyEncephalitisbusinessEncephalitis

description

Systemic protothecosis is an exceptionally rare cause of sepsis with few available therapeutic options. Here, we report on a female patient with newly diagnosed acute myeloid leukemia who died after start of chemotherapy due to a severe septic shock caused by a disseminated systemic infection with Prototheca zopfii including encephalitis.

10.1016/j.mmcr.2021.01.004http://www.sciencedirect.com/science/article/pii/S221175392100004X