6533b7dbfe1ef96bd1270c62

RESEARCH PRODUCT

Gingival hyperplasia as an early manifestation of acute myeloid leukemia. A retrospective review

Javier Flores-fraileNansi López-valverdeRafael Gómez De DiegoJorge Muriel-fernándezJuan M. RamírezAntonio López-valverde

subject

Retrospective reviewmedicine.medical_specialtyAcute myeloblastic leukemiabusiness.industryResearchMyeloid leukemia030206 dentistry030204 cardiovascular system & hematologyOral healthHyperplasiamedicine.disease:CIENCIAS MÉDICAS [UNESCO]GastroenterologyCommunity and Preventive DentistryDyscrasiaGingival enlargement03 medical and health sciences0302 clinical medicineInternal medicineCorrelation analysisUNESCO::CIENCIAS MÉDICASmedicinebusinessGeneral Dentistry

description

Background We study the prevalence of acute myeloid leukemia (AML) among patients with severe gingival enlargement. Material and Methods We retrospective reviewed the clinical records of patients with severe gingival enlargement, between 2011 and 2018. The Saxer and Mühlemann index were used to measure inflammation and gingival bleeding. The degree of dental mobility was measured by the Nyman and Lindhe technique. Results A correlation analysis was carried out to test whether there were any associations among the different variables. In the sample of 117 patients the mean gingival bleeding index was ≥3 and the degree of dental mobility ≥2.3. 1.7% of patients, with severe gingival hyperplasia were diagnosed with AML. We found a significant association between gingival bleeding and aging (p<0.001) and a trend (0.54) between bleeding and suffering from AML. Conclusions Severe gingival enlargement, abundant gingival bleeding, and dental mobility could be early manifestations of a blood dyscrasia. Key words:Acute myeloblastic leukemia, gingival hyperplasia, bleeding, tooth motility, oral health.

yearjournalcountryeditionlanguage
2019-12-01
https://hdl.handle.net/10550/72894