6533b7dbfe1ef96bd127129d
RESEARCH PRODUCT
Muscle Biopsy; Processing and Evaluation
W. StenzelH.h. Goebelsubject
Muscle tissuePathologymedicine.medical_specialtyMuscle biopsyNeuromuscular diseasemedicine.diagnostic_testEnzyme histochemistrySkeletal muscleHistologyBiologymedicine.diseasemedicine.anatomical_structureNeedle biopsymedicineImmunohistochemistrydescription
Muscle biopsy is a diagnostic procedure to recognize myopathological lesions in skeletal muscle. It may be an open surgical procedure or performed by needle biopsy. The muscle biopsy ought to target a myopathologically affected muscle, chosen by clinical features and/or myoimaging. Preparative techniques entail histology, electron microscopy, enzyme histochemistry, and immunohistochemistry, but it is essential to leave additional tissue for possible subsequent biochemical and molecular investigations. The backbone of light microscopic, diagnostic studies is unfixed frozen muscle tissue with cross-sectioned muscle fibers. Correct archiving of biopsied muscle tissue for future diagnostic and research studies is mandatory.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2014-01-01 |