6533b7dbfe1ef96bd1271373

RESEARCH PRODUCT

Versuche zur Bestimmung des wahren K-Efflux im Rattenzwerchfell

subject

description

In an isolated muscle loaded with 42K the potassium efflux through the muscle fibre membrane can be calculated from the rate constant of the loss of 42K into an inactive bathing solution. The calculation can only be valid if the amount of 42K leaving all the individual fibres is equivalent to the amount of 42K entering the bathing solution from the surface of the whole muscle. It seems possible that 42K ions which have already left a muscle cell can be taken up again into a muscle fibre before diffusing into the bathing solution. Thus the calculated potassium efflux might be smaller than the real efflux.