6533b7dbfe1ef96bd12714ed

RESEARCH PRODUCT

Involvement of the chromosomal region 11q13 in renal oncocytoma: case report and literature review.

Michael StöckleTrijnie DijkhuizenH.j. DeckerE. Van Den BergChristine NeuhausChristoph HuberStephan StörkelB. Mensch

subject

Cancer Researchmedicine.medical_specialtyPathologyChromosomes Human Pair 21Chromosomes Human Pair 20Chromosomal translocationChromosome DisordersBiologyurologic and male genital diseasesTranslocation GeneticGeneticsmedicineAdenoma OxyphilicHumansOncocytomaRenal oncocytomaCYTOGENETIC ABNORMALITIESMolecular BiologyAgedGeneticsChromosome AberrationsChromosomes Human Pair 11CytogeneticsChromosomeLOCALIZATIONKaryotypemedicine.diseaseTUMORSGENEKidney NeoplasmsChromosome BandingChromosomal regionFemaleAbnormalityChromosomes Human Pair 9

description

Renal oncocytomas comprise a cytogenetically heterogeneous group of tumors consisting potentially of cytogenetic distinguishable subgroups. Review of the literature revealed loss of chromosome 1 and Y as a possible anomaly for at least one subset of oncocytomas. The frequent finding of rearrangements involving chromosome 11 band q13 characterizes another subset of oncocytomas. We report the cytogenetic and pathological features of a renal oncocytoma diagnosed in a 72-year-old woman and found a t(9;11)(p23;q13) as a consistent abnormality. This supports the idea that translocations involving 11q13 define a further subset of oncocytoma. (C) Elsevier Science Inc., 1997.

yearjournalcountryeditionlanguage
1997-04-01Cancer genetics and cytogenetics
10.1016/s0165-4608(96)00205-1https://pubmed.ncbi.nlm.nih.gov/9109935