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RESEARCH PRODUCT

Cytogenetic study of angiosarcoma of the breast.

Pilar SorianoConcha López-ginésSergio AlmenarAntonio Llombart-boschCarlos VázquezRosario Gil-benso

subject

Chromosome AberrationsCancer Researchmedicine.medical_treatmentCarcinoma Ductal BreastHemangiosarcomaCancerBreast NeoplasmsNeoplasms Second PrimarySegmental MastectomyBiologyMiddle Agedmedicine.diseasedigestive system diseasesRadiation therapyInfiltrating ductal carcinomaKaryotypingGeneticsCancer researchmedicineHumansAngiosarcomaFemaleneoplasms

description

Angiosarcoma of the breast is quite rare, and the development of cutaneous angiosarcoma after segmental mastectomy and radiation therapy is even less common. A cytogenetic analysis of a mammary angiosarcoma arising in a breast after previous irradiation and segmental mastectomy for infiltrating ductal carcinoma revealed multiple clonal rearrangements involving chromosomes X, 1, 2, 3, 4, 5, 6, 7, 8, 9, 15, 17, 20, and 22. No cytogenetically analyzed angiosarcomas of the breast have been reported before. Genes Chromosom Cancer 10:210–212 (1994). © 1994 Wiley-Liss, Inc.

yearjournalcountryeditionlanguage
1994-07-01Genes, chromosomescancer
10.1002/gcc.2870100311https://pubmed.ncbi.nlm.nih.gov/7522046