6533b7dcfe1ef96bd1271dd1

RESEARCH PRODUCT

Lessons Learned from the German Registry for Acute Aortic Dissection Type A (GERAADA) and Expectations for the Future

Ernst WeigangMaria BlettnerTobias Krüger

subject

Aortic dissectionmedicine.medical_specialtybusiness.industryGeneral surgeryPreoperative riskmedicine.diseaseAortic arch surgerylanguage.human_languageSurgeryGermanlanguageMedicineObservational studySources of errorbusinessNeurological impairmentNeurological deficit

description

The German Registry for Acute Aortic Dissection type A (GERAADA) is a prospective observational clinical multicenter registry that was launched in 2006. With more than 2,500 patients included from over 50 recruiting centers it is—to our knowledge—the most representative register for acute aortic dissection type A (AADA) currently available. We examined mortality and post-operative events as well as the influence of various pre- and intraoperative factors on these endpoints. Among patients registered, 30-day mortality is 15.9 %. 13.4 % of patients experienced postoperatively a new neurological deficit and a total of 10.5 % of patients suffered from permanent neurological impairment 30 days after surgery. Results concerning preoperative risk factors, the extent of the aortic arch surgery, techniques of cerebral protection and aortic dissection surgery in the elderly patients have been published and will be summarized here. Furthermore, the aims and rationales of aortic registries are defined. In special sections we describe the methodology of aortic registries, critically discuss possible sources of error and limitations of the approach and we suggest future perspectives for studying AADA.

yearjournalcountryeditionlanguage
2014-01-01
https://doi.org/10.1007/978-1-4471-5622-2_15