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6533b7dcfe1ef96bd1272bec

RESEARCH PRODUCT

CD73 Overexpression in Podocytes: A Novel Marker of Podocyte Injury in Human Kidney Disease

Berthold HocherAlexander MarxFelix BestvaterStefan PorubskyStefan PorubskyRaoul BergnerChristian LöfflerBernhard K. KrämerDamir KrunicZoran V. Popovic

subject

Male0301 basic medicinePathologyCCR2podocyte030232 urology & nephrologyGene ExpressionKidneyPodocyte0302 clinical medicineFocal segmental glomerulosclerosisMedicineMinimal change diseaseBiology (General)5'-NucleotidaseSpectroscopyAged 80 and overKidneymedicine.diagnostic_testPodocytesGlomerulonephritisGeneral MedicineMiddle AgedComputer Science ApplicationsChemistryProteinuriaminimal change diseasemedicine.anatomical_structureImmunohistochemistryFemaleKidney DiseasesAdultmedicine.medical_specialtyQH301-705.5Receptors CCR2GPI-Linked ProteinsImmunofluorescenceArticleCatalysisInorganic Chemistry03 medical and health sciencesHumansPhysical and Theoretical ChemistryQD1-999Molecular BiologyAgedbusiness.industryOrganic Chemistrymedicine.disease030104 developmental biologyGene Expression RegulationCD73CCR2businessBiomarkers

description

The CD73 pathway is an important anti-inflammatory mechanism in various disease settings. Observations in mouse models suggested that CD73 might have a protective role in kidney damage

yearjournalcountryeditionlanguage
2021-07-01International Journal of Molecular Sciences
https://doi.org/10.3390/ijms22147642
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