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RESEARCH PRODUCT
Bladder Mucosal Graft Vaginoplasty: A Case Report
Flavia TripiF. CataliottiElettra VestriCinzia ChiaramonteAntonino Giulio GiannoneMarcello Cimadorsubject
medicine.medical_specialtyVaginoscopyAdolescentUrinary Bladder030232 urology & nephrologyDSDIntroitusGraft03 medical and health sciencesGynecologic Surgical Procedures0302 clinical medicineGynecologic Surgical Procedure030225 pediatricsHumansMedicineChildDiversion colitisUrinary bladderMucous Membranebusiness.industryVirilizationUrogenital AbnormalitieInfant NewbornObstetrics and GynecologyInfantGeneral Medicinemedicine.diseaseBladder mucosaSurgerymedicine.anatomical_structureTreatment OutcomeVaginoplastyUrogenital AbnormalitiesChild PreschoolPediatrics Perinatology and Child HealthVaginaVaginaVaginoplastyFemalemedicine.symptomVaginal hypoplasiaUrogenital sinubusinessHumandescription
Abstract Background Female vaginoplasty reconstruction, by choice, is usually performed with adjacent tissue. However in some clinical conditions such as high urogenital confluence sinus, cloacal malformation with extreme vaginal hypoplasia, local tissue may not be available. When vaginal replacement is performed in pediatric patients intestinal segments is preferred to non-operative procedures that require continuative dilations. However mucus production, malignant transformation risk and diversion colitis are important side effects. Technique We present a nouvel technique for vaginoplasty in a female child presenting with an isolated urogenital sinus malformation without virilization. The patient at 20 months underwent vaginoplasty using tubularized bladder mucosal graft. Results Surgical procedure was devoid of complications. Pubertal development occurred at age of 15. She underwent regular follow up until 18 years of age. At this age we performed clinical evaluation: absence of vaginal introitus stenosis and good cosmetic results were observed. Then she underwent vaginoscopy with multiple biopsies. Pathology examination of the bladder mucosal graft evidenced a normal structure of the mucosa, with a stratified squamous epithelium. Discussion Different techniques are taken into account for vaginal reconstruction according to the severity and to the type of malformation. We describe the use of bladder mucosal graft with favorable results after long term follow-up.
year | journal | country | edition | language |
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2018-10-01 |