6533b7ddfe1ef96bd1273cdb

RESEARCH PRODUCT

A new ceramide from the leaves of Lannea schimperi (Hochst. ex A.Rich.) Engl.

Augustin Silvere NgouelaPierre TaneTill OpatzElise Vanessa N TemgouaBlanche Laure NdontsaGabin Thierry M. BitchagnoGabin Thierry M. BitchagnoRoukayatou MbouangouereRolande Tsafack NguemoRoland T. TchuenguemJames D. Simo Mpetga

subject

chemistry.chemical_classificationReactive oxygen speciesCeramideChromatographybiology010405 organic chemistryDPPHOrganic ChemistryPlant Sciencebiology.organism_classification01 natural sciencesBiochemistry0104 chemical sciencesAnalytical Chemistry010404 medicinal & biomolecular chemistrychemistry.chemical_compoundColumn chromatographychemistryLannea schimperiAnacardiaceaeMethanol

description

A new ceramide is being reported herein together with six known compounds from the methanol extract of the leaves of Lannea schimperi (Hochst. ex A.Rich.) Engl. The metabolites were obtained through repeated open column chromatography and were characterized by spectroscopic and spectrometric techniques. The radical-scavenging activity of the crude extract and isolated compounds was evaluated using the DPPH radical. The obtained results suggest the studied species as prominent candidate to fight reactive oxygen species (ROS).

https://doi.org/10.1080/14786419.2020.1789632