6533b7ddfe1ef96bd12740ab

RESEARCH PRODUCT

Hemolytic uremic syndrome in an infant following Bordetella pertussis infection.

F. CastellettiIvana PelaD. SeraciniAlfredo CaprioliAnna Giammanco

subject

Microbiology (medical)Hemolytic anemiaPediatricsmedicine.medical_specialtyBordetella pertussisWhooping CoughPertussis toxinBordetella pertussislaw.inventionMedical microbiologylawmedicineHumansbiologybusiness.industryInfantGeneral Medicinebiology.organism_classificationmedicine.diseaseIntensive care unitInfectious DiseasesHemolytic-Uremic SyndromeImmunologyParoxysmal coughFemalebusinessKidney disease

description

Reported here is the case of a 6-week-old female infant with a severe Bordetella pertussis infection requiring supportive pressure-positive ventilation in the intensive care unit. After being discharged from the intensive care unit, she developed hemolytic anemia, thrombocytopenia and acute renal failure, which suggested a diagnosis of hemolytic uremic syndrome. The clinical outcome was favorable with no renal consequences. This case suggests there may be a direct cause-effect relationship between B. pertussis infection and hemolytic uremic syndrome.

http://hdl.handle.net/10447/4215